Arterial Stiffness for Improved Prediction of Coronary Artery Disease by Coronary CT Angiography

Launched by DANDERYD HOSPITAL · Dec 12, 2024

Keywords

ClinConnect Summary

This clinical trial is focused on improving the way doctors predict coronary artery disease, a condition that affects blood flow to the heart and can cause chest pain and shortness of breath. The study will explore how well a device that measures arterial stiffness, along with advanced computer techniques, can help identify patients who may have this condition more accurately.

To participate in this trial, you need to be between 30 and 70 years old and be undergoing a specific heart scan called coronary CT angiography to check for suspected coronary artery disease. However, individuals with a known history of heart disease, certain serious heart or lung conditions, or those who cannot give consent cannot take part. If you join, you can expect to have your arterial stiffness measured and to contribute to research that could improve future heart health assessments. The trial is currently recruiting participants, and your involvement could help shape better diagnosis and treatment options for others.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients undergoing coronary computer tomography angiography to investigate stable suspected symptomatic coronary artery disease.
• • Age 30 to \<70 years of age.
• Exclusion Criteria:
• • Known coronary artery disease (prior myocardial infarction, percutaneous coronary intervention, coronary artery bypass graft or any angiographic evidence of coronary artery disease ≥50% lesion in a major epicardial vessel).
• • Known significant cardiac (\> moderate valvular disease, heart failure with reduced ejection fraction, hypertrophic cardiomyopathy, or congenital heart disease), or pulmonary condition which could explain symptoms.
• • Known ongoing atrial fibrillation/flutter.
• • No Swedish social security number.
• • Unable to provide written informed consent.