Ciprofol Based on Total Intravenous Anesthesia During Pediatric Laparoscopic Surgery

Launched by TONGJI HOSPITAL · Dec 11, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a type of anesthesia called ciprofol to see how well it works during pediatric laparoscopic surgeries, which are minimally invasive operations often used to treat conditions like hernias and appendicitis in children. The goal is to determine if total intravenous anesthesia (anesthesia given through an IV) is just as effective and safe as other methods currently used. This study will not start recruiting participants just yet, but when it does, it will include children aged 2 to 12 years who need laparoscopic surgery under general anesthesia.

To participate, children must not have certain health issues, such as known allergies to the study medications or serious problems with their breathing, heart, liver, or kidneys. They should also not have participated in other studies recently. If eligible, children will receive either ciprofol or another type of anesthesia without knowing which one they got, helping researchers fairly compare the two. This trial aims to ensure that the anesthesia used is safe and effective for young patients during their surgeries.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • laparoscopic surgery under general anesthesia
• Exclusion Criteria:
• • Known allergies to propofol and ciprofol,
• • Mental retardation, cognitive and affective disorders, psychiatric or neurological disorders;
• • uncooperate with peripheral venipuncture and catheterization;
• • History of acute upper respiratory tract infection in the past 2 weeks;
• • With severe respiratory, circulation, liver and kidney insufficiency;
• • Body mass index (BMI) of 30 kg/m² or 15 kg/m²;
• • Known long-term use of sedative drugs;
• • ASAⅢ grade or above;
• • recent participation in other clinical studies.