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Search / Trial NCT06738888

Renovated Prediction Model for Difficult Transoral and Submental Endoscopic Thyroidectomy

Launched by SHANGHAI 6TH PEOPLE'S HOSPITAL · Dec 13, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Endoscopic Thyroidectomy Transoral And Submental Approach Prediction Model

ClinConnect Summary

This clinical trial is focused on improving a prediction model for a type of thyroid surgery called transoral and submental endoscopic thyroidectomy. This surgery is done through the mouth and under the chin, which can be less invasive than traditional methods. The researchers previously developed a model to help identify which patients might have difficulties during this surgery, and now they want to update and test this model in a new group of patients. The goal is to make this approach more effective and to help train future surgeons.

To be eligible for this trial, participants should have a diagnosis of differentiated thyroid cancer or a benign thyroid nodule that is not too large. Specifically, the cancer should be no bigger than 4 cm, and the nodule no larger than 6 cm. Importantly, there should be no signs of cancer spreading to nearby lymph nodes or other parts of the body. People who have had previous neck surgery, have certain neck conditions, or show signs of cancer invading beyond the thyroid may not be able to participate. If you join the trial, you can expect to help researchers learn more about which patients can benefit most from this less invasive surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Clinical diagnosis of differentiated thyroid cancer with a maximum diameter not exceeding 4 cm
  • Clinical diagnosis of benign thyroid nodule with a maximum diameter not exceeding 6 cm
  • Absence of suspicious lateral lymph nodes or distant metastases
  • Exclusion Criteria:
  • Participants with fusion or fixation of lymph nodes in the neck
  • Participants with history of neck surgery or radiation
  • Participants with vocal fold fixation by preoperative fibrolaryngoscope
  • Participants with preoperative examination suggestive of extrathyroidal invasion
  • Participants with a significantly restricted neck and/or jaw

About Shanghai 6th People's Hospital

Shanghai 6th People's Hospital is a leading medical institution in China, renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital focuses on a wide range of therapeutic areas, striving to enhance patient outcomes and contribute to medical knowledge. With a dedicated team of experienced researchers and clinicians, Shanghai 6th People's Hospital emphasizes rigorous scientific methodology and ethical standards, ensuring that all trials are conducted with the utmost integrity and patient safety in mind. Through collaboration with various stakeholders, the hospital aims to bridge the gap between clinical research and real-world application, ultimately improving healthcare delivery both locally and globally.

Locations

Shanghai, , China

Patients applied

0 patients applied

Trial Officials

Ling Zhan, Doctor

Principal Investigator

Shanghai 6th People's Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported