Genetic Determinants of Exercise-Induced Muscle Damage (POLYGENDOMUS)

Launched by LILLE UNIVERSITY · Dec 13, 2024

Keywords

ClinConnect Summary

The POLYGENDOMUS trial is a research study that aims to understand how our genes might influence muscle damage that can occur after exercise. Specifically, the study will look at changes in a substance called CPK in the blood, which can indicate muscle damage, before and after engaging in intense physical activity. The researchers are looking to include 300 healthy participants aged between 18 and 35 who are members of a sports club recognized by an Olympic federation.

If you are eligible, you can expect to undergo some exercise testing and provide blood samples at different times to help the researchers gather data. It’s important for participants to be in good health and willing to follow all study procedures. Those with certain medical conditions, current treatments, or who are not affiliated with an Olympic sports club will not be able to join the study. This trial is a great opportunity to contribute to the understanding of how our genetic makeup affects our response to exercise.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male or female
• • Aged between 18 and 35
• • Weighing more than 50 kg
• • Member of a sports club affiliated to an Olympic federation
• • Socially insured
• • Willing to comply with all study procedures and duration of the study
• Exclusion Criteria:
• • Medical history contraindicating sporting activities
• • Current medical treatment
• • Not a member of a sports club affiliated to an Olympic federation
• • Administrative reasons: impossibility of receiving informed information, impossibility of participating in the entire study, absence of social security coverage, refusal to sign consent form.