Difference Between Monofilament Versus Multifilament Suture Material in Isthmocele Formation

Launched by AIN SHAMS MATERNITY HOSPITAL · Dec 17, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different types of sutures used during a cesarean section (C-section) can affect the healing of the uterine scar. Specifically, it compares monofilament sutures, which are made of a single strand, to multifilament sutures, which are made of multiple strands twisted together. The main goal is to find out which type of suture leads to more scar tissue formation in the uterus after surgery. Additionally, the trial will look at other factors like how much blood loss occurs during surgery and whether extra stitches are needed to control bleeding.

To participate in this trial, women aged 20 to 45 who are having their first C-section for a single baby, between 37 and 42 weeks of pregnancy, may be eligible. However, those with a history of previous uterine surgeries or certain medical conditions will not be included, as these factors could influence the results. Participants can expect to be part of a study that seeks to improve surgical outcomes and healing for future mothers. This trial is currently recruiting, and it's an opportunity to contribute valuable information that could help guide best practices in cesarean surgeries.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age: 20-45 years old
• • Singleton pregnancy.
• • Gestational age between 37 completed weeks to 42 weeks.
• • Patients undergoing elective primary caesarean section
• Exclusion Criteria:
• • History of uterine surgery (e.g. hysterotomy, myomectomy, perforation, caesarean section). (to be able to differentiate between the recent CS scar and the old scar)
• • Abnormal placental invasion (placenta previa and accrete ) ( more liable to undergo Cesarean hysterectomy)
• • Uterine anomalies (e.g., septum, Mullerian anomalies or fibroids). (may be localized at the suture line and therefore affect the scar)
• • Drugs intake that affects bleeding or tissue healing e.g., anti-coagulants, immunosuppressive drugs and chronic use of steroids (more than 14 days pre-operative)
• • Any medical Co-morbidity (diabetes mellitus, Hypertension and Thyroid abnormalities) (more liable to affect the healing)