A Study of Mitral Annular Disjunction in Mitral Valve Prolapse Patients and Arrhythmia Risk

Launched by ASSIUT UNIVERSITY · Dec 15, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a condition called mitral annular disjunction in patients who have mitral valve prolapse, which is when the heart's mitral valve doesn't close properly. The study aims to understand how common this condition is in patients with severe mitral regurgitation, where blood leaks backward into the heart. It will take place at Assiut University Heart Hospital and is not yet recruiting participants.

To be eligible for this study, participants need to be adults over 18 years old who have been diagnosed with mitral valve prolapse and have severe mitral regurgitation. However, individuals who have had previous mitral valve surgery, have certain other heart conditions, or have poor-quality heart images will not be included. Those who participate can expect to undergo assessments to help researchers learn more about the link between these heart conditions and the risk of arrhythmias, which are irregular heartbeats.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All consecutive patients \> 18 years of age presenting to Assiut University Heart Hospital with MVP and more than moderate MR.
• Exclusion Criteria:
• • Previous mitral valve surgery.
• • MVP due to infective endocarditis.
• • Moderate or more significant aortic stenosis, aortic regurgitation or mitral stenosis.
• • Congenital heart disease and poor image quality precluding accurate assessment of the mitral valve.