Adding Magnesium Sulfate or Dexmedetomidine to Bupivacaine in Oblique Subcostal Tap Block for Laparoscopic Cholecystectomy: a Randomized Double -Blind Controlled Study

Launched by ASSIUT UNIVERSITY · Dec 17, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at ways to help manage pain after a common surgery called laparoscopic cholecystectomy, which is the removal of the gallbladder. The researchers want to see if adding two different medications, magnesium sulfate or dexmedetomidine, to a pain-relieving medicine called bupivacaine can improve pain control for patients after the surgery. The goal is to find out which combination works better to keep patients comfortable during the first 24 hours after their operation.

To participate in this study, you need to be between 18 and 60 years old and scheduled for elective gallbladder surgery. You should be in good health, without serious medical conditions or a history of chronic pain. If you join the trial, you will receive one of the pain relief combinations, and the medical team will monitor your pain and how well the treatments work. This research is important because managing pain effectively can help patients recover faster and may prevent long-term pain complications after surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • • Patients programmed for elective LC.
• • American society of anesthesiologists (ASA) physical state I or II.
• • Age over 18 years and less than 60 years old.
• • Patients of both sex are included in the study.
• Exclusion Criteria:
• • •Patient refusal
• • Known hypersensitivity to the study drugs.
• • Body Mass Index \> 40 kg/m2.
• • Inability to accurately describe postoperative pain to investigators.
• • Opioid tolerance or dependence.
• • Preexisting history of chronic pain.
• • History of renal, liver, cardiac, neuropsychiatric disorder problems.
• • Bleeding or coagulation abnormality.