Dual-function Semirigid Thoracoscopy Versus Semirigid Thoracoscopy for the Diagnosis of Pleural Diseases: A Multicenter Open-label Randomized Controlled Trial

Launched by CHINA-JAPAN FRIENDSHIP HOSPITAL · Dec 19, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at two different types of tools used to diagnose pleural diseases, which are conditions affecting the space around the lungs. Researchers have developed a new tool called a dual-function semirigid thoracoscope, which can take tissue samples more effectively than a standard semirigid thoracoscope. The goal of the study is to compare how well these two tools work in diagnosing pleural diseases, focusing on how accurate the results are, how safely the samples are taken, and how easy they are to use.

To participate in this trial, individuals must be at least 18 years old and have a specific type of fluid buildup in the chest that doctors need to investigate further. However, those with certain health issues, like serious breathing problems or uncontrolled bleeding, may not be eligible. If someone joins the study, they can expect to undergo a procedure where one of these tools will be used to collect samples from their pleural space. This trial is still in the planning stages, so they are not yet recruiting participants, but it aims to provide valuable insights into the best ways to diagnose these conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Unilateral pleural effusion of unclear etiology after a less invasive diagnosis
• • Fully informed of the purpose and method of the study, agreed to participate in the study, and signed an informed consent form.
• Exclusion Criteria:
• • PaO2/FiO2 \< 300
• • Tendency for uncontrolled bleeding, unstable cardiovascular status, or severe heart failure
• • A complete pleural symphysis, where it is not possible to create a pneumothorax
• • Refractory cough
• • Eastern Cooperative Oncology Group performance status 4
• • Disagreements regarding study participation
• • Participation in other studies within three months without withdrawal or termination.