Hop Compounds on the Immune System in Overweight People

Launched by UNIVERSITY OF VIENNA · Dec 17, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how certain compounds found in hops, called Iso-alpha Acids and Xanthohumol, affect the immune system in overweight individuals. The researchers want to see if these substances can help improve the body's response to inflammation, which can be important for people with early signs of metabolic diseases.

To participate in the study, you should be between 65 and 74 years old and have a body mass index (BMI) of 25 to 29.9, which indicates being overweight. You should also have at least one of the following conditions: pre-diabetes, fatty liver, or high-normal blood pressure. If you have certain medical conditions, like inflammatory bowel disease or cancer of the gastrointestinal tract, or if you're on specific medications, you may not be eligible to join. Participants will be closely monitored and can expect to learn more about how these hop compounds might benefit their health. If you're interested in improving your immune response and meet the eligibility criteria, this could be a great opportunity to consider.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • BMI 25 - 29,9 kg/m²
• as well as one or more of the following incipient metabolic diseases:
• • pre-diabetes (fasting blood glucose 100-125 mg/dL),
• • fatty liver (grade 1-3),
• • high-normal blood pressure to mild hypertension (grade 1, systolic 140-159 mmHg)
• Exclusion Criteria:
• • History of diseases that could falsify the study results
• • inflammatory bowel diseases
• • malignant diseases of the gastrointestinal tract
• • food allergies
• • malabsorption
• • kidney or liver disease (except simple fatty liver)
• • symptomatic heart failure
• • Taking medication to treat these diseases
• • Consumption of special diets (e.g. vegan, gluten-free)
• • Pregnancy