Myocardial Infarction and Periodontitis: Periodontal Health Intervention.

Launched by SHANGHAI 10TH PEOPLE'S HOSPITAL · Dec 17, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how treating gum disease, or periodontitis, can help patients who have had a heart attack, specifically a type called ST-segment elevation myocardial infarction (STEMI). Researchers want to gather information from patients with both conditions to see if improving their oral health can lead to better heart health outcomes. The study aims to create a comprehensive database that can help in understanding the connection between oral health and heart disease, ultimately promoting better clinical practices.

To participate in this trial, you need to be at least 30 years old and have been diagnosed with a STEMI heart attack along with severe gum disease, which is characterized by specific dental measurements. This includes having significant gum loss and bleeding when your gums are checked by a dentist. If you qualify and choose to join, you will be contributing to important research that may benefit future patients with similar health issues. It's also important to know that certain conditions, like being pregnant, having specific diseases, or significant tooth loss, may prevent you from participating in the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * 1)Patients diagnosed with ST-segment elevation myocardial infarction (STEMI). 2)Patients with severe periodontal disease, defined as:
• • 5 teeth with clinical attachment loss (CAL) ≥ 4 mm.
• • Subgingival probing depth (PD) ≥ 6 mm. ③≥ 8 teeth with gingival bleeding on probing (BOP). 3）Age ≥30 years. 4）Written informed consent provided.
• Exclusion Criteria:
• • 1) under 30 years old; 2) HIV positive, chronic inflammation, tumor disease, drug dependence, use of anticonvulsants, use of immunosuppressive agents, pregnancy, and lactation; 3) significant tooth loss (number of remaining teeth \< 8); 4) long hospital stay (\>10 days), new myocardial infarction before randomization, and stent thrombosis; 5) Refusal to sign informed consent.