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Search / Trial NCT06745648

Carotid Sinus Massage in Trendelenburg Position for Headache Relief

Launched by HOSPITAL MUNICIPAL PEDRO T. ORELLANA · Dec 17, 2024

Trial Information

Current as of June 28, 2025

Recruiting

Keywords

Carotid Sinus Massage Trendelenburg Autonomic Nervous System

ClinConnect Summary

The C-SMART trial is studying a new way to help relieve headaches, specifically migraines and tension-type headaches. Researchers believe that a technique called carotid sinus massage (CSM), combined with a specific body position known as the modified Trendelenburg position, may help reduce headache pain. This study aims to see if this method can provide immediate relief for people suffering from headaches.

To participate in this trial, individuals must be experiencing migraines or tension-type headaches. However, there are some health conditions that would prevent someone from joining, such as certain heart issues or a history of strokes. If eligible, participants will receive CSM while lying in the modified Trendelenburg position, and this will be done up to three times, with a short break in between. Before and after the treatment, participants will rate their pain on a simple scale. This trial is currently not recruiting participants, but it aims to offer a potential new option for those looking for relief from their headaches.

Gender

ALL

Eligibility criteria

  • INCLUSION CRITERIA:
  • Participants must be at least 16 years of age.
  • * Must have a diagnosis of one of the following, according to the International Classification of Headache Disorders (ICHD-3):
  • Migraine
  • Tension-type headache
  • Mixed headache
  • The headache episode must have started within the past 24 hours.
  • EXCLUSION CRITERIA:
  • * Any contraindication to carotid sinus massage, including:
  • Carotid bruits
  • Recent myocardial infarction
  • History of stroke
  • Known or suspected carotid artery stenosis
  • * Any contraindication to the Trendelenburg position, including:
  • Increased intracranial pressure
  • Respiratory distress
  • Congestive heart failure
  • History of syncope
  • History of cardiac arrhythmias

About Hospital Municipal Pedro T. Orellana

Hospital Municipal Pedro T. Orellana is a reputable healthcare institution dedicated to advancing medical knowledge and improving patient outcomes through innovative clinical research. With a focus on patient-centered care, the hospital conducts a variety of clinical trials aimed at exploring new treatment options and enhancing existing therapies. The institution boasts a multidisciplinary team of experienced healthcare professionals and researchers committed to ethical standards and regulatory compliance. By fostering collaboration and utilizing state-of-the-art facilities, Hospital Municipal Pedro T. Orellana plays a pivotal role in contributing to the advancement of medical science and the betterment of community health.

Locations

Trenque Lauquen, Buenos Aires, Argentina

Patients applied

0 patients applied

Trial Officials

Pablo D Anaya, MD

Principal Investigator

Hospital Municipal Pedro T. Orellana

Heberto J Suarez-Roca, MD, PhD

Study Director

Dule University Medical Center, Dept. of Anesthesiology, Center for Translational Pain Medicine

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported