Phosphatidylethanol and Other Ethanol Consumption Markers

Launched by THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO · Dec 18, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a specific marker in the blood called phosphatidylethanol, which may help researchers understand how much alcohol people drink and the patterns of their drinking. The goal is to use this information to improve future programs aimed at preventing alcohol misuse and helping those who need treatment.

To participate in the study, you need to be at least 21 years old, have a healthy weight, and have drunk alcohol on more than one day in the last month, reaching a blood alcohol level of around 0.06% at least once. If you join, you'll visit the lab to drink alcohol in a controlled setting, where your blood will be taken multiple times over a few hours and again in the following weeks. The study is currently looking for volunteers, and your contributions could help others in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. are ≥ 21 years old;
• • 2. are height and weight proportionate (body mass index 18-30); and
• • 3. report drinking on \> 1 days in the last month, with at least one day equal to at least achieving \~0.06% BAC.
• Exclusion Criteria:
• • 1. have significant current or predicted alcohol withdrawal symptoms (CIWA-AR scores ≥ 10);
• • 2. are currently in alcohol treatment;
• • 3. have substance use disorder (except nicotine, and/or caffeine);
• • 4. have a medical condition that would contraindicate participation (a positive urine pregnancy test, self-reported scheduled surgery or liver disease);
• • 5. are currently breast feeding;
• • 6. have a presence of a DSM-5 psychiatric disorder with symptoms of psychosis and/or delirium; or
• • 7. are unable to comprehend the informed consent process or study instructions.