General vs Spinal in Total Joint Arthroplasty (TJA)

Launched by UNIVERSITY OF MIAMI · Dec 18, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring the differences in recovery outcomes for patients undergoing total joint replacement surgery for hip or knee osteoarthritis. Specifically, the researchers want to see how different types of anesthesia—general anesthesia (where you are fully asleep) versus spinal anesthesia (which numbs the lower body)—affect things like how long patients stay in the hospital, their pain levels after surgery, and the risk of complications such as infections or needing additional surgeries.

To participate in this study, patients should be between 65 and 74 years old and should be preparing for their first total hip or knee replacement surgery. They also need to be able to understand and give consent to participate, and they should speak either English or Spanish. However, certain health issues could prevent someone from joining, such as serious heart conditions or previous surgeries on the spine. If you decide to participate, you can expect close monitoring and support throughout your recovery journey as researchers gather important information to help improve future patient care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients undergoing a primary total hip or knee arthroplasty
• • Subjects must be capable of providing informed consent
• • English or Spanish speaking
• Exclusion Criteria:
• Patients with contraindications for spinal anesthesia such as:
• • Prior lumbar surgery with hardware insertion
• • Elevated intracranial pressure
• • Infection at the site of the procedure
• • Thrombocytopenia or coagulopathy
• • Severe mitral and aortic stenosis and left ventricular outflow obstruction
• • Severe spine pathology (spinal stenosis, spondylolisthesis, spondylosis) with radiculopathy and/or neurogenic claudication
• • Preexisting neurological disease
• Patients with contraindications for general anesthesia such as:
• • Congestive heart failure
• • Severe aortic stenosis
• • Patient is unable/unwilling to consent
• • Current pregnancy or women planning on becoming pregnant in the next year, and women who think they might be pregnant, or women who become pregnant during the study period will be removed from the study.
• • Prisoners