Effect of Transcutaneous Electrical Nerve Stimulation Based on Wrist-ankle Acupuncture Theory on EC50 of Remifentanil Inhibiting Responses to Tracheal Intubation Under General Anesthesia

Launched by CHANGHAI HOSPITAL · Dec 23, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new approach to help manage pain and stress during a medical procedure called tracheal intubation, which is commonly done under general anesthesia. The researchers want to see if a method called Transcutaneous Electrical Nerve Stimulation based on Wrist-Ankle Acupuncture theory (TENS-WAA) can effectively reduce the amount of a pain medication, remifentanil, needed during this procedure. TENS-WAA is a non-invasive treatment that uses electrical stimulation to help relieve pain without the need for needles, making it a safer and easier option for patients.

To participate in this study, individuals need to be between 18 and 64 years old, have a body mass index (BMI) of 30 or less, and be in generally good health (ASA grade I-III). However, those with certain conditions, such as difficult airways, severe heart disease, or those who have had recent acupuncture, will not be eligible. Participants will be closely monitored during the trial and can expect to help researchers understand how effective this new method is in improving comfort during anesthesia. This information could be important for better pain management in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged 18-64 years old;
• • ASA grade I-Ⅲ;
• • BMI≤30kg/m2.
• Exclusion Criteria:
• • Patients predicted to have difficult airways or those experiencing unsuccessful intubation processes;
• • Individuals with psychiatric disorders, cognitive impairments, or other conditions that preclude cooperation;
• • Patients who have received acupuncture treatment within the past three months or are undergoing routine acupuncture therapy;
• • Individuals with a history of severe cardiovascular disease, hyperthyroidism, or asthma;
• • Patients with contraindications to transcutaneous electrical nerve stimulation (TENS), including those with pacemakers, metallic implants, allergies to surface electrodes, skin sensory disorders, skin lesions, scars, or unhealed adhesions.