Radiographic and Histological Assessment of GBR Using DBB Compared to Spontaneous Bone Regeneration of Maxillary Defects , Resulted from Enucleation of Intra-bony Cystic Lesions

Launched by CAIRO UNIVERSITY · Dec 23, 2024

Keywords

ClinConnect Summary

This clinical trial is studying two different ways to help patients with defects in the upper jaw (maxilla) caused by the removal of cysts. One group of patients will receive a technique called guided bone regeneration, which helps the body grow new bone in a controlled way. The other group will rely on the body’s natural ability to heal and regenerate bone on its own. The goal is to compare how well these two methods work for rebuilding the bone in the affected area.

To be eligible for this trial, participants should be between 20 and 50 years old and have specific kinds of cyst-related defects in their jaw that are between 1.5 and 4.0 cm wide. They should be in good health, without any conditions that could hinder healing, and not pregnant or breastfeeding. If you join the study, you will receive treatment and attend regular check-ups to monitor your progress. This trial is currently looking for participants, so if you or someone you know fits the criteria, it could be a valuable opportunity to contribute to medical research while receiving care for your condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Pathological Maxillary intra-bony defects with diameter ranging from 1.5 to 4.0 cm.
• • patients indicated for implant placement after teeth extraction.
• • Age range from 20-50 years.
• • Patients free from any systemic conditions and bone metabolism diseases that might interfere with the surgical intervention, soft tissue or hard tissue healing.
• • No evidence of acute inflammation.
• • Regular attendance at control visits.
• Exclusion Criteria:
• • Pregnancy or lactation.
• • Systemic conditions that compromise bone healing such as : uncontrolled diabetes mellitus, history of chemotherapy or radiotherapy or Hematological disorders.
• • Patients taking bisphosphonates, glucocorticoids or other drugs that may interfere with bone metabolism.
• • presence of infection at the surgical site.
• • infected cysts and odontogenic keratocyst.