Comparison of Endoscopic Lumbar Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion(MIS-TLIF) for Degenerative Lumbar Spondylolisthesis

Launched by QUEEN SAVANG VADHANA MEMORIAL HOSPITAL, THAILAND · Dec 18, 2024

Keywords

ClinConnect Summary

This clinical trial is studying two different surgical treatments for a condition called degenerative lumbar spondylolisthesis, which occurs when one of the bones in the lower back slips out of place. The trial will compare a traditional surgery called Minimally Invasive Transforaminal Lumbar Interbody Fusion (MIS-TLIF) with a newer, less invasive approach called Endoscopic Lumbar Decompression. This research aims to see which method works better for patients who have not found relief from their symptoms through non-surgical treatments for at least three months.

To be eligible for this trial, participants should have a single level of low-grade degenerative spondylolisthesis and no significant instability in their spine. They should also be willing to follow up for at least a year after the surgery. Unfortunately, individuals with severe spinal issues, previous spine surgeries, or certain other medical conditions may not qualify. This trial is not yet recruiting participants, but it promises to offer valuable insights into the best surgical options for those suffering from this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Single level lumbar degenerative spondylolisthesis (Meyerding Grading Grade I or II).
• • Failed conservative treatment for at least 3 months.
• • No instability evidence of levels of lesion (Consideration from translation more than 5 mm or angulation change more than 10 degree in flexion and extension L-S plain films ).
• • Able to follow up for at least 12 months.
• • Patient who vorantarily agree to participate in research.
• Exclusion Criteria:
• • Patients with severe foraminal stenosis diagnosed by MRI.
• • Patients who have previously undergone lumbar spine surgery (revision surgery).
• • Patients with other abnormalities in the lumbar spine, such as infection, tumors, or fractures.
• • Patients who cannot undergo surgery due to underlying conditions or who cannot maintain the prone position for extended periods.