Quantitative Neurofeedback Techniques for Treating Perioperative Cognitive Disorders in Elderly Patients

Launched by CANCER INSTITUTE AND HOSPITAL, CHINESE ACADEMY OF MEDICAL SCIENCES · Dec 21, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether a special training method called neurofeedback can help prevent confusion and cognitive problems in elderly patients undergoing major surgery. Specifically, the researchers want to find out if this training can reduce the occurrence of postoperative delirium, which is a state of confusion that can happen after surgery. Patients will participate by completing neurofeedback training for about 14 hours in the two weeks leading up to their surgery. Their cognitive function will be assessed both before and after surgery, and they will be monitored daily for any signs of delirium for a week after the operation.

To be eligible for this trial, participants must be 65 years or older and scheduled for elective major surgery that lasts more than two hours. Certain conditions, such as severe organ dysfunction or prior surgeries that could affect communication after the operation, will exclude potential participants. It’s important for patients and their families to know that this trial is not yet recruiting, but it aims to provide valuable insights into improving recovery for elderly patients undergoing surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients undergoing elective major surgery (colorectal, pancreatic-gastric, hepatobiliary, thoracic, gynaecological and urological) under general anaesthesia;
• • Expected duration of surgery \>2 hours;
• • Age ≥65 years;
• Exclusion Criteria:
• • refused to participate in this study;
• • preoperative MMSE score \<26 or if the patient's educational level was lower than high school, MMSE \<24 and active depressive state (GDS-15 score \>9);
• • underwent neurosurgery or the surgery itself interfered with the patient's postoperative communicative communication (e.g., tracheotomy);
• • severe organ dysfunction;
• • underwent cardiac surgery, (e) Undergoing cardiac surgery, neurosurgery, or neurosurgery;
• • ASA classification IV or higher.