Labetalol Infusion and Dexmedetomidine Infusion in Hypotensive Anesthesia

Launched by AIN SHAMS UNIVERSITY · Dec 21, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring two different medications, Labetalol and Dexmedetomidine, to see which one works better for keeping blood pressure low during certain ear, nose, and throat surgeries. This situation, known as hypotensive anesthesia, helps reduce bleeding during surgery, making it easier for doctors to see what they’re doing. The trial is specifically looking for patients who are healthy enough for surgery, aged between 20 and 50 years, and who meet certain medical criteria.

To participate, patients must not have serious heart or blood pressure issues, and they should not be pregnant or breastfeeding. If someone decides to join the study, they can expect to receive one of the two medications during their surgery, and their blood pressure will be closely monitored. This research is important because it aims to find the safest and most effective way to manage blood pressure for these types of procedures, potentially improving outcomes for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • American Society of Anesthesiologists I, II (ASA I, II) patients who were candidate for Ear, Nose and Throat surgeries.
• • Age: between 20 and 50 years
• Exclusion Criteria:
• • Patients with uncontrolled hypertension, variable degrees of heart block, congestive cardiac failure, coagulopathy, cerebral insufficiency, hepatic or renal abnormality
• • Patients on beta blocker or clonidine
• • Pregnant or lactating females
• • Patients who were allergic to any of the anesthetic or hypotensive drugs used in the study
• • Patient refusal to be included in the trial