Personalised Prevention of Microbiological Homeostasis in the Oral Cavity During Fixed Orthodontic Treatment

Launched by CENTRE HOSPITALIER UNIVERSITAIRE DE NICE · Dec 20, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how personalized prevention strategies can help maintain a healthy balance of bacteria in the mouth during orthodontic treatment, such as braces. When patients wear braces, it can be harder to keep their teeth clean, leading to an imbalance of bacteria, known as dysbiosis. The trial will involve two groups: one will receive personalized prevention strategies tailored to their specific needs, while the other will follow standard care without these personalized measures. The goal is to see if the personalized approach can help prevent dysbiosis and keep the mouth healthier throughout treatment.

To participate, patients must be between 12 and 20 years old and need fixed orthodontic treatment (like braces). However, individuals with certain conditions, such as untreated cavities or weakened immune systems, cannot join. If selected for the trial, participants can expect regular check-ups and personalized advice on how to maintain their oral health during their orthodontic treatment. This study aims to create better prevention strategies that could eventually benefit all patients undergoing orthodontic care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 12 to 20 (permanent dentition) requiring fixed orthodontic treatment.
• Exclusion Criteria:
• • Tobacco;
• • Overcrowded restorations, untreated caries,
• • lack of tooth mineralisation;
• • Medical pathologies;
• • Known immunodepression (congenital or acquired);
• • Taking a treatment that may induce general immunodepression;
• • Taking a probiotic;
• • Taking a concomitant treatment that may interact with oral health