Electrochemotherapy (ECT) in Patients With Primary Visceral Tumors and/or Secondary Visceral Localizations, of Any Histotype

Launched by ISTITUTO ONCOLOGICO VENETO IRCCS · Dec 20, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring a treatment called electrochemotherapy for patients with certain types of tumors in their organs, known as visceral tumors. These can include cancers like liver cancer, pancreatic cancer, and melanoma, among others. Electrochemotherapy combines a special drug called bleomycin with electrical pulses to help make cancer cells more sensitive to the medicine, aiming to improve the response of tumors that cannot be removed with surgery. The trial will gather information on how well this treatment works for patients whose tumors are not treatable with standard methods.

To participate in the study, you need to be an adult (18 years or older) diagnosed with primary or secondary visceral tumors that cannot be surgically removed. You should also be able to understand the treatment and agree to participate by signing a consent form. However, if you have certain health issues, like severe lung problems or are pregnant, you may not be eligible. Participants will receive the treatment in a controlled medical setting, and the study aims to assess the safety and effectiveness of this innovative approach for managing difficult-to-treat cancers.

Gender

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Eligibility criteria

• Inclusion Criteria:
• • Male/Female ≥ 18 years
• • Ability to understand the proposed treatment and express an informed acceptance by signing the informed consent
• • Diagnosis of primary and/or secondary visceral localizations of any histotype
• • Patients who are not eligible for standard curative procedures
• Exclusion Criteria:
• • Absolute contraindications to invasive procedures
• • Concomitant presence of brain, lung, bone metastases
• • Uncorrectable coagulation changes
• • Bleomycin allergy
• • Absolute contraindications to taking Bleomycin
• • Poor respiratory function or pulmonary fibrosis
• • Acute lung infections
• • Is pregnant or breastfeeding or expecting to conceive or father children within the projected duration of the study