Diagnostic Feasibility of 100 Hz Tetanic Stimulation

Launched by UNIVERSITY OF DEBRECEN · Dec 23, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a method called 100 Hz tetanic stimulation to see if it can help doctors determine if patients still have muscle weakness after surgery. This weakness, known as a postoperative residual neuromuscular block, can happen when anesthesia affects muscle function. The study will focus on patients who are either healthy or have certain conditions affecting their nerves, and it will measure how their muscles respond to this specific stimulation while they are under anesthesia.

To participate in the trial, individuals should be between the ages of 65 and 74, generally healthy (with a body weight that’s considered normal), and able to lie on their back with one arm easily accessible for testing. However, people with certain muscle or nerve diseases, those taking specific medications that affect muscle function, pregnant or breastfeeding women, and those having emergency surgeries cannot join. Participants can expect to be monitored during the study, and their muscle responses will be carefully recorded to help improve understanding of muscle function during and after anesthesia.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ASA 1-3;
• • BMI 18.5-25 (normal body weight);
• • patient is in supine position with one arm accessible.
• Exclusion Criteria:
• • diseases with impaired neuromuscular function (myopathies, severe liver and kidney failure);
• • drugs affecting neuromuscular function (magnesium, aminoglycosides);
• • pregnancy (pregnancy tests are carried out in women of childbearing age to rule out pregnancy);
• • breast-feeding;
• • acute surgery