Exocrine Pancreatic Insufficiency and Functional Dyspepsia

Launched by MARIA MARTA PISKORZ · Jan 1, 2025

Keywords

ClinConnect Summary

This clinical trial is looking to understand how common a condition called exocrine pancreatic insufficiency (EPI) is in people who have functional dyspepsia, which is a type of digestive problem that causes symptoms like stomach pain and bloating. Researchers want to find out how many patients with functional dyspepsia also have EPI and what specific characteristics these patients might have. To do this, participants will be evaluated for their symptoms and will have a simple test to measure certain enzymes in their stool. If the initial results suggest EPI, they may undergo further tests, including an ultrasound, to determine the cause.

To participate in this study, individuals must be over 18 years old and diagnosed with functional dyspepsia, with no other underlying digestive or serious health issues. They should also not be pregnant or breastfeeding and must be able to give informed consent. This trial is not yet recruiting participants, but it aims to gather important information that could help improve understanding and treatment for people dealing with these digestive issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients over 18 years of age diagnosed with functional dyspepsia based on Rome IV criteria, who have been excluded for organic, metabolic, and medication-related causes (NSAIDs), and who test negative for H. pylori.
• Exclusion Criteria:
• • Pregnancy or lactation
• • Organic diseases of the digestive tract (celiac disease, inflammatory bowel diseases, neoplasms, positive for H. pylori)
• • Uncontrolled systemic diseases (diabetes mellitus, hypo- or hyperthyroidism, cancer, etc.)
• • Lack of informed consent
• • Severe psychiatric disorders, defined based on the DSM-5