Conventional Vs Tailored Limb Lengths in Laparoscopic Roux-en Y Gastric Bypass Surgery

Launched by GEM HOSPITAL & RESEARCH CENTER · Dec 30, 2024

Keywords

ClinConnect Summary

This clinical trial is studying two different approaches to a type of weight-loss surgery called Laparoscopic Roux-en-Y Gastric Bypass (LRYGB). The goal is to see if customizing the lengths of certain parts of the surgery leads to better weight loss and health improvements compared to the standard lengths used in most surgeries. Participants will be divided into two groups: one will receive the usual limb lengths (75 cm and 125 cm), while the other will have their limb lengths adjusted based on their individual small bowel length.

To be eligible for this study, you need to be between 18 and 65 years old and have a Body Mass Index (BMI) of 40 or higher, or a BMI of 35 or higher with at least one obesity-related health issue, such as diabetes or high blood pressure. Participants will be closely monitored after the surgery to track weight loss, changes in BMI, and any improvements in related health conditions. It’s important to note that some people may not qualify, such as those with previous weight-loss surgeries or certain serious health conditions. If you’re interested, you’ll need to provide written consent and agree to follow the study’s guidelines.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age: 18-65 years
• 2. Body Mass Index (BMI):
• • BMI ≥ 40 kg/m² or BMI ≥ 35 kg/m² with at least one obesity-related comorbidity (e.g., type 2 diabetes, hypertension, obstructive sleep apnea).
• • 3. ASA - less than or equal to 3
• • 4. Informed Consent: Ability and willingness to provide written informed consent and comply with procedures.
• • 5. Previous Weight Loss Attempts: Documentation of previous attempts at weight loss through diet, exercise, or medical management.
• Exclusion Criteria:
• • 1. Previous Bariatric Surgery: Prior bariatric or major gastrointestinal surgery that might affect the outcome of RYGB.
• • 2. Severe Cardiopulmonary Conditions: Significant cardiac or pulmonary conditions that pose a high surgical risk (e.g., severe congestive heart failure, severe chronic obstructive pulmonary disease).
• • 3. Uncontrolled Psychiatric Disorders: Severe psychiatric illness or substance abuse issues that are not well-controlled, including eating disorders.
• • 4. Pregnancy: Current pregnancy or plans to become pregnant within 12 months post-surgery.
• • 5. Malignancy: Active malignancy or history of malignancy requiring treatment in the past 5 years (excluding non-melanoma skin cancer).
• • 6. Severe Liver Disease: Cirrhosis or significant liver dysfunction (e.g., Child-Pugh B or C).
• • 7. Inability to Comply: Patients who are unable or unwilling to comply with the postoperative follow-up schedule and dietary requirements.
• • 8. Chronic Use of Medications: Chronic use of medications known to affect weight or metabolism significantly, such as corticosteroids or antipsychotics.
• • 9. Other Medical Conditions: Any other medical condition or surgical finding that, in the opinion of the investigators, would make the patient unsuitable for the study.