Long-Term Outcomes of Different Surgical Techniques for Sacral Tarlov Cysts: A Prospective Cohort Study

Launched by BEIJING JISHUITAN HOSPITAL · Dec 24, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different surgical techniques can help adults aged 18 to 75 years who have painful sacral Tarlov cysts, which are fluid-filled sacs located near the lower spine. The researchers want to find out if one type of surgery is better than the others for relieving pain and improving everyday activities, as well as how often problems come back or complications arise after surgery. Participants will have one of three surgical options and will be followed for up to two years to see how well they recover.

To be eligible for this study, individuals must be diagnosed with symptomatic sacral Tarlov cysts through MRI and have symptoms like persistent lower back pain, numbness, or issues with bowel, bladder, or sexual function. They should not have had prior surgery for these cysts or other serious health conditions that could complicate the surgery. Participants will be assessed before and after their surgery to track their pain levels and overall recovery. This trial is still in the planning stages and has not yet started recruiting participants.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• • 1. Age 18-75 years.
• • 2. Diagnosed with symptomatic sacral Tarlov cysts confirmed by MRI.
• 3. Presence of at least one of the following symptoms:
• • Persistent sacral or lower back pain (VAS score ≥ 4).
• • Neurological deficits such as lower extremity numbness or weakness.
• • Bowel, bladder, or sexual dysfunction attributable to the cyst.
• • 4. Eligible for surgical intervention based on clinical evaluation.
• • 5. Willing and able to provide written informed consent.
• • Exclusion Criteria
• • 1. History of prior sacral Tarlov cyst surgery.
• • 2. Concurrent spinal conditions requiring separate surgical intervention.
• • 3. Active infection or systemic inflammatory disease.
• • 4. Severe comorbidities that increase surgical risk (e.g., advanced cardiac or pulmonary disease).
• • 5. Pregnancy or lactation.
• • 6. Inability to comply with follow-up requirements.
• • 7. Known allergy or contraindication to surgical materials (e.g., fibrin glue).