Central Motor Mechanisms in AIS Via HD-sEMG, EEG and Neuromuscular Coupling Analysis

Launched by THE FIRST AFFILIATED HOSPITAL OF ZHEJIANG CHINESE MEDICAL UNIVERSITY · Dec 26, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how spinal manipulation affects motor control in adolescents with Idiopathic Scoliosis, a condition where the spine curves abnormally without a known cause. Researchers want to see if this type of treatment can help improve muscle function and trunk stability in these patients. They will use advanced technology to measure how the brain and muscles communicate before and after treatment, helping to understand how spinal manipulation may improve movement and control.

To participate in this study, you must be at least 10 years old and have specific characteristics related to your scoliosis, such as a certain degree of curvature in your spine. You should also not have had any previous treatments for your condition. If eligible, participants can expect to receive standardized spinal manipulation treatments and will be assessed using various tests to evaluate improvements in muscle function and balance. It's important to note that those with severe health issues or who have already received other treatments that could affect the results will not be able to join the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients aged ≥10 years;
• • 2. Risser sign grade 0-3;
• • 3. Cobb angle between 10° and 40°;
• • 4. No prior treatment;
• • 5. Female patients within 1 year after menarche or before menstruation;
• • 6. The patient's guardian signs the informed consent form for treatment.
• Exclusion Criteria:
• • 1. Those who do not meet the diagnostic criteria for AIS or inclusion criteria;
• • 2. Patients with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney, and hematopoietic system disorders, or those with mental illnesses;
• • 3. Patients with thrombocytopenia, coagulation disorders, or a tendency to bleed;
• • 4. Patients who are afraid of the treatment and cannot tolerate it;
• • 5. Those who have already received other treatments that may affect the study's outcome measures.