HoLEP Vs BipolEP in Management of BPH Patients with Large Prostates

Launched by ASSIUT UNIVERSITY · Jan 3, 2025

Keywords

ClinConnect Summary

This clinical trial is comparing two different procedures for treating men with a condition called benign prostatic hyperplasia (BPH), which means an enlarged prostate. Specifically, the trial is looking at the effectiveness of bipolar enucleation of the prostate versus holmium laser enucleation of the prostate. The goal is to see if the bipolar method can provide similar benefits as the laser method, especially in hospitals that may not have all the resources available.

To be eligible for this trial, participants must be men over 50 years old with prostate volumes larger than 80 ml and who have had difficulty with other medications. They should also have significant urinary problems, such as having trouble urinating or needing a catheter. However, men with certain conditions, like urinary infections or prostate cancer, will not be able to participate. If you join the trial, you'll be closely monitored to see how well the treatments work and to ensure your safety throughout the process. This trial is not yet recruiting participants, but it aims to provide valuable information for future treatment options for men with large prostates.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Age \>50 years
• • Prostate volume \>80 ml
• • Failure of or noncompliance with medical treatment
• • IPSS \>15
• • Qmax \<15 ml/sec
• • Urinary retention and fixed catheters with poor results on trial of voiding without catheter
• Exclusion Criteria:
• • Patients with active UTI
• • Prostate cancer
• • Bladder carcinoma
• • Urethral stricture
• • Neurogenic bladder disorders
• • Redo cases