Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Myocardial Injury in Elderly Patients Undergoing Thoracoscopic Surgery: a Prospective, Randomized Controlled Study
Launched by AFFILIATED HOSPITAL OF JIAXING UNIVERSITY · Dec 29, 2024
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
A small number of studies based on transcutaneous auricular vagus nerve stimulation have shown that it has good therapeutic effects on patients with cardiovascular disease, and is simple to operate, with few complications and low risks. However, thoracic surgery is closer to the heart and has a higher incidence of perioperative myocardial injury. , and hs-cTnT has become a biomarker that predicts myocardial injury. This research group plans to design a prospective, double-blind, randomized controlled study to explore the effect of taVNS on hs-cTnT in elderly patients undergoing thoracoscopi...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Aged ≥60 years old
- • 2. Inpatients scheduled to undergo elective thoracoscopic lobectomy, segmentectomy, or wedge resection
- • 3. ASA score of Ⅰ-Ⅲ
- • 4. Able to communicate with the researcher Communicate and cooperate with patients completing assessment scales.
- Exclusion Criteria:
- • 1. Patients with congenital heart disease, coronary heart disease, myocardial infarction, severe heart block or implanted cardiac pacemaker
- • 2. Patients with neurological diseases such as cerebral infarction, cerebral hemorrhage or stroke
- • 3. Patients with pain, damage, infection or unhealed ear trauma in the area near the external auricle
- • 4. Patients with a history of severe mental illness, abuse of analgesia or addiction to psychiatric drugs
- • 5. Patients with severe digestive system diseases
- • 6. Patients and their families who refuse surgical anesthesia or are unable to cooperate in completing the questionnaire
- • 7. Pregnant women.
About Affiliated Hospital Of Jiaxing University
The Affiliated Hospital of Jiaxing University is a leading medical institution dedicated to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the hospital focuses on a wide range of therapeutic areas, leveraging its state-of-the-art facilities and a team of experienced healthcare professionals. Committed to improving patient outcomes, the hospital engages in rigorous scientific studies that adhere to the highest ethical standards and regulatory guidelines. Through collaboration with academic institutions and industry partners, the Affiliated Hospital of Jiaxing University aims to contribute significantly to medical knowledge and enhance treatment options for diverse patient populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Jiaxing, Zhejiang, China
Patients applied
Trial Officials
Qinghe Zhou
Principal Investigator
Jiaxing University Affiliated Hospital
Mingzi An, MD
Study Director
Jiaxing University Affiliated Hospital.
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported