Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermatosis

Launched by NANJING FIRST HOSPITAL, NANJING MEDICAL UNIVERSITY · Jan 2, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a special facial mask made with Centella Asiatica, a plant known for its healing properties, on skin conditions like rosacea, acne, and melasma. The goal is to find out if this mask can safely help improve these skin issues. Participants in the study will be randomly assigned to receive either the Centella mask or a control mask on each side of their face for 8 weeks, allowing researchers to compare the results.

To join the study, participants need to be at least 18 years old and have mild to moderate symptoms of rosacea, acne, or melasma. They should be in generally good health and not currently taking any medications that could affect the study. Women who are pregnant, breastfeeding, or have certain skin conditions may not be eligible. Throughout the trial, participants will be closely monitored, and they will need to follow the study's treatment guidelines to help ensure accurate results.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Meet mild to moderate rosacea, acne diagnostic criteria; Meet the diagnostic criteria for melasma;
• • 2. Over 18 years of age;
• • 3. Be able to follow the treatment rules of the study and be followed for 8 weeks;
• • 4. Informed consent; 5There were no significant cardiac, liver, kidney, gastrointestinal, neurological, psychiatric, or metabolic disorders
• • 6.No medication was used within 1 month
• Exclusion Criteria:
• • 1. Currently pregnant, planning to become pregnant or breastfeeding;
• • 2. Documented hypersensitivity to any active ingredient or excipient included in the study drug, or a history of adverse reactions to cosmetic products;
• • 3. Participate in other clinical studies within 3 months before the start of the study;
• • 4. Frequent use of Chinese medicine, sleeping pills, sedatives, anti-anxiety drugs or potentially addictive substances;
• • 5. Present with concomitant skin conditions that may confuse the clinical assessment of rosacea, melasma, seborrheic dermatitis or pose a risk to participants, or have a history of severe skin conditions;
• • 6. Normal use of relevant treatment (including intense pulsed light, pulsed fuel laser, oral and topical tranexamic acid, oral tetracycline antibiotics, oral compound glycyrrhizin and other anti-inflammatory drugs)
• • 7. Patients with incomplete observation data, incomplete course of treatment and inability to take drugs as prescribed by doctors were removed