Comparison of Safety and Efficacy for Different Sedation Regimens During Colonoscopy

Launched by QASSIM HEALTH CLUSTER · Jan 6, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the safety and effectiveness of different sedation methods used during a colonoscopy, a procedure where doctors look inside the colon using a flexible tube called a colonoscope. Sedation helps patients feel relaxed and comfortable, reducing any pain or discomfort during the procedure. The study will take place at King Saud Hospital in Saudi Arabia and aims to find out which sedation options work best for patients undergoing this type of procedure.

To participate in the trial, you must be an adult between 18 and 60 years old and be in good health, as determined by a doctor. Individuals with certain medical conditions, allergies to specific sedation medications, or those who are pregnant or have a high body weight may not be eligible. If you join the study, you can expect to receive either one of the sedation methods being compared, but you won't know which one you’re getting. The goal is to ensure that you have a safe and comfortable experience during your colonoscopy.

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • Adults aged 18-60 years
• • Both Genders
• • Indication of colonoscopy procedure without advanced intervention
• • American Society of Anesthesiologists (ASA) physical status I or II
• • Competent to give informed consent
• * Exclusion criteria:
• • Personal history of allergic reaction or other contra-indications to midazolam, propofol or fentanyl
• • Age below 18 or above 60 years
• • Chronic use of benzodiazepines
• • ASA physical status III or above
• • Pregnancy
• • History of smoking or alcohol abuse
• • Body mass index \> 35 kg/m2
• • History of airway obstruction or difficult intubation