Impact of Atorvastatin Versus Rosuvastatin on 25 Hydroxy Vitamin D Levels in Patients With Acute Coronary Syndrome

Launched by KING EDWARD MEDICAL UNIVERSITY · Jan 3, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of two different medications, atorvastatin and rosuvastatin, on Vitamin D levels in patients who have experienced acute coronary syndrome, a serious heart condition. The trial will involve two groups of patients, each receiving one of the medications for six months. The researchers want to see if either drug can help raise Vitamin D levels in participants.

To be eligible for this study, participants must be between the ages of 65 to 74 and have been diagnosed with acute coronary syndrome. They should also have Vitamin D levels that fall between 30-70 ng/ml. However, people who are pregnant, breastfeeding, or have certain medical conditions or have taken specific medications recently will not be able to participate. If you join the study, you will be monitored closely to see how the medication affects your Vitamin D levels over time. This research could provide valuable insights into how these medications can impact heart health and Vitamin D status.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Acute Coronary Syndrome
• • 25 OH-Vitamin D levels between 30-70ng/ml
• Exclusion Criteria:
• • Hypercalcemia
• • hypocalcemia
• • pregnancy
• • lactation
• • hypersensitivity to statins
• • hypothyroidism
• • Deranged LFTs \& RFTs
• • Use of following within last 3 months (Vitamin D Supplements, lipid lowering drugs, anti-obesity drugs, corticosteroids)