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Search / Trial NCT06766006

ECMO LEft Ventricle UNloading Strategy

Launched by MAASTRICHT UNIVERSITY MEDICAL CENTER · Jan 3, 2025

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Extracorporeal Membrane Oxygenation Left Ventricle Unloading Cardiogenic Shock Cardiac Arrest Mechanical Circulatory Supports

ClinConnect Summary

The ECMO Left Ventricle Unloading Strategy trial is an important study looking at how to better support patients who are critically ill and using a treatment called veno-arterial extracorporeal life support (VA ECLS). This treatment helps patients whose hearts are not pumping blood effectively, often due to conditions like shock or cardiac arrest. The trial aims to understand how the heart’s left ventricle can become overloaded during this treatment and to explore different methods to relieve this pressure. Researchers will collect data from many hospitals around the world to compare the effectiveness of various strategies for unloading the left ventricle and to see how these strategies affect patient outcomes.

Anyone aged 1 to 29,219 who is receiving VA ECLS may be eligible to participate in this study, as long as they are not undergoing other forms of ECMO (a different type of life support). Participants will contribute to a large international effort to gather valuable information that could improve care for patients in similar situations. If you or a loved one are considering participating, you can expect to be part of a study that may help shape future treatments for patients with serious heart conditions.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All patients undergoing VA ECLS will be enrolled.
  • Exclusion Criteria:
  • Patients without VA ECMO will not be considered

About Maastricht University Medical Center

Maastricht University Medical Center (MUMC+) is a leading academic medical center in the Netherlands, renowned for its commitment to advancing healthcare through innovative research and education. As a prominent sponsor of clinical trials, MUMC+ integrates cutting-edge scientific inquiry with clinical practice, focusing on a wide range of medical disciplines. The center emphasizes collaboration among multidisciplinary teams, fostering an environment that promotes excellence in patient care and the translation of research findings into clinical applications. MUMC+ is dedicated to improving health outcomes and enhancing quality of life through rigorous clinical investigations and the development of novel therapeutic strategies.

Locations

Maastricht, , Netherlands

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported