Chios Mastic Toothpaste and Halitosis and Oral Hygiene in Orthodontic Patients

Launched by UNIVERSITY OF ATHENS · Jan 3, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a special toothpaste made from mastic, a resin from the mastic tree, on bad breath (halitosis) and oral hygiene in teenagers who are undergoing orthodontic treatment with braces. The researchers want to see if using this toothpaste can reduce bad breath by measuring certain compounds related to it and also improve the cleanliness of teeth and gums in these young patients.

To participate in the trial, you need to be between 13 and 18 years old and currently wearing traditional braces on your upper and lower teeth for at least four months. You should also be in good health and have a specific level of bad breath as indicated by tests. However, you won't be eligible if you have dental issues like cavities or gum disease, smoke, have certain allergies, or have taken specific medications recently. If you join this study, you'll be helping researchers learn more about how mastic toothpaste can benefit young people with braces in keeping their mouths fresh and healthy.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• Patients eligible for the trial must comply with all of the following at randomization:
• • • Age between 13 and 18 years for the group with conventional orthodontic appliances.
• • This age group represents the majority of patients seeking orthodontic treatment and is homogeneous regarding occupational status (high-school and lyceum students in Greece). Younger patients might present with cooperation problems.
• • Good general health.
• • Orthodontic fixed labial appliances on the maxillary and mandibular arch, brackets at least on 20 teeth for more than 4 months before enrollment and estimated duration of the treatment more than 1 month, bands on the first molars, extraction cases patients could be enrolled at least two months after the last extraction.
• • Total initial VSCs levels above the baseline level of 150ppb.
• Exclusion Criteria:
• Patients will be excluded for any of the following reasons:
• • Active caries
• • Periodontitis
• • Dental fluorosis / dysplasia of the teeth
• • Syndromes, mental disabilities and craniofacial deformities
• • Smoking or use of other tobacco products
• • Allergy to mastic
• • Antibiotics during the last 2 months
• • Chlorhexidine in the previous 3 weeks
• • Participation in other trials