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Search / Trial NCT06767371

Success of Pulpotomy in Molars with Pulpitis with Periodontitis Detected Using AI and Those Without Periodontitis

Launched by MISR INTERNATIONAL UNIVERSITY · Jan 5, 2025

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Full Pulpotomy Apical Periodontitis Radiography X Ray Periapical Radiolucency Mature Permanent Molars Artificial Intelligence Irreversible Pulpitis Wolter's Classification Severe Pulpitis Moderate Pulpitis Vital Pulp Therapy

ClinConnect Summary

This clinical trial is studying the effectiveness of a dental procedure called pulpotomy, which is used to treat severe tooth pain caused by irreversible pulpitis. The researchers want to compare the success of pulpotomy in patients with moderate pulpitis who do not have a condition called apical periodontitis (which affects the tip of the tooth root) to those with severe pulpitis who do have this condition. They will also evaluate a new artificial intelligence (AI) technology that helps detect apical periodontitis in dental X-rays to see how accurate it is compared to traditional methods.

To participate, individuals must be between 20 and 45 years old and have mature permanent molars diagnosed with either moderate irreversible pulpitis (without apical periodontitis) or severe irreversible pulpitis (with apical periodontitis). Participants will receive either pulpotomy or the standard root canal treatment, and their progress will be monitored through follow-up visits at 1, 3, and 6 months after the procedure. This study aims to improve treatment options for patients with severe tooth pain and enhance the accuracy of detecting dental conditions using AI technology.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Presence of vital mature permanent molars diagnosed as severe irreversible pulpitis with apical periodontitis diagnosed clinically and radiographically and cases diagnosed as moderate irreversible pulpitis without apical periodontitis diagnosed clinically and radiographically per Wolter's classification.
  • Participants of both genders falling within the age range of 20 to 45 years.
  • Confirmation of vital bleeding pulp tissue in all canals following complete pulpotomy.
  • Exclusion Criteria:
  • Non-vital tooth
  • Moderate pulpitis with apical periodontitis
  • Teeth with Immature roots
  • Uncontrolled pulpal bleeding persisting beyond 10 minutes post-application of sodium hypochlorite as a hemostatic agent.
  • Insufficient bleeding post-pulp exposure, indicative of pulp degeneration.
  • Cases categorized as initial and mild pulpitis per Wolter's classification.

About Misr International University

MISR International University is a distinguished educational institution dedicated to advancing health sciences and clinical research. As a clinical trial sponsor, the university emphasizes innovative methodologies and rigorous scientific standards to enhance the quality of healthcare solutions. Committed to fostering collaboration between academia and industry, MISR International University actively engages in clinical trials that aim to address pressing medical challenges while ensuring ethical practices and patient safety. Through its comprehensive approach, the university seeks to contribute significantly to the body of clinical knowledge and improve health outcomes in the community.

Locations

Cairo, Obour, Egypt

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported