The Comparison of Tunnel Morphology and Graft Healing in Anterior Cruciate Ligament Reconstructions Using Peroneus Longus And Hamstring Tendons
Launched by KARADENIZ TECHNICAL UNIVERSITY · Jan 7, 2025
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at two different types of grafts used in surgeries to repair a torn anterior cruciate ligament (ACL) in the knee. Specifically, it compares grafts made from hamstring tendons and those made from the Peroneus Longus tendon. The researchers want to see how well these grafts heal and integrate with the bone over time by using advanced imaging techniques like Magnetic Resonance Imaging (MRI) and Computerized Tomography (CT). They are particularly interested in whether the healing process and effects on the knee differ between the two graft types and if these differences relate to the patients' overall health.
To participate in this study, candidates must be between 18 and 45 years old, have a body mass index (BMI) between 18 and 28, and have a confirmed ACL injury through an MRI. However, individuals with a history of previous knee or ankle surgeries, multiple ligament injuries, severe osteoporosis, or certain types of meniscal injuries may not be eligible. Participants in the trial can expect to undergo imaging tests and be monitored for their recovery progress. This study is currently recruiting, and it aims to provide valuable insights into the best options for ACL reconstruction surgery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients aged between 18 and 45 years.
- • BMI in the range of 18 to 28.
- • Diagnosed with an anterior cruciate ligament (ACL) injury preoperatively confirmed by MRI.
- • Patients for whom it is deemed appropriate to harvest ipsilateral hamstring tendons or Peroneus Longus tendon for use as a graft.
- Exclusion Criteria:
- • History of previous surgery on the affected knee or ankle.
- • Presence of multiple ligament injuries in the affected knee.
- • Diagnosis of advanced osteoporosis.
- • ACL injuries that occurred more than 12 months prior to surgery.
- • Evidence of unstable meniscal injury on preoperative MRI, which may alter the postoperative rehabilitation process.
- • Evidence of unstable meniscal injury on preoperative MRI, which may alter the postoperative rehabilitation process.
About Karadeniz Technical University
Karadeniz Technical University is a prestigious academic institution located in Trabzon, Turkey, renowned for its commitment to advancing research and education in the fields of science and technology. As a clinical trial sponsor, the university leverages its extensive resources, expertise, and collaborative networks to conduct innovative research that enhances healthcare outcomes. With a focus on ethical standards and rigorous methodologies, Karadeniz Technical University aims to contribute valuable insights to medical science and improve patient care through well-designed clinical studies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Trabzon, , Turkey
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported