Effect of Ultrasound-assisted Lung Recruitment Maneuver on Preventing Perioperative Atelectasis
Launched by ISTANBUL UNIVERSITY - CERRAHPASA · Jan 9, 2025
Trial Information
Current as of November 10, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
This study is testing whether using ultrasound to guide a lung-reopening technique at the end of surgery can help reduce lung collapse (atelectasis) and related breathing problems in children. Involving kids aged 1 to 14 who are having surgery that is expected to take at least 2 hours, participants are randomly put into three groups: Group 1 receives a standard small amount of breathing support (PEEP) during the operation; Group 2 gets the same support plus a short “recruitment maneuver” at the end of surgery to reopen any collapsed airways; Group 3 gets the same standard support plus a similar maneuver performed while the child lies on their side. The lungs will be checked with ultrasound before anesthesia, shortly after induction, before the end-of-surgery maneuver, and shortly after extubation to measure lung appearance and any blocks in air flow. Researchers will monitor heart rate, blood pressure, oxygen levels, and other breathing-related measures during surgery and for 24 hours afterward.
Eligible children include those 1–14 years old with an ASA health status of 1–3 and a planned surgery lasting at least 2 hours. Exclusions include more serious heart or lung conditions, a history of prematurity with lung problems, cystic fibrosis, certain chest or spine issues, previous chest surgery, or procedures done with a laparoscope. The study is randomized and double-blind (the child and some researchers don’t know which group the participant is in). Results are not yet available. It is being conducted at Istanbul University-Caerrahpasa in Turkey, with about 78 participants planned and results expected in early 2025.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients aged 1 to 14 years
- • ASA scores of 1 to 3
- • Minimum surgical duration of 2 hours.
- Exclusion Criteria:
- • Patients with an ASA score of 4,
- • Defined lung diseases (such as those using medication for asthma and having a hospital visit within the past year)
- • Prematurity ( bronchopulmonary dysplasia)
- • Cystic fibrosis
- • Diagnosed syndromic conditions
- • Congenital cardiac disease
- • Abnormal lung findings
- • Chest wall deformities
- • A history of chest surgery
- • Those undergoing laparoscopic surgery
About Istanbul University Cerrahpasa
Istanbul University - Cerrahpasa is a prestigious academic institution renowned for its commitment to advancing medical research and education. With a focus on innovative clinical trials, the university harnesses cutting-edge methodologies to address pressing health challenges. Its collaborative environment fosters interdisciplinary research, enabling the development of effective therapeutic strategies and enhancing patient care. The institution's dedication to ethical standards and patient safety underscores its reputation as a leader in clinical research within the region and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Istanbul, Turkey
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported