Investigation of Central Sensitization and Associated Factors in Patients With Lipedema

Launched by SULTAN ABDULHAMID HAN TRAINING AND RESEARCH HOSPITAL, ISTANBUL, TURKEY · Jan 7, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a condition called lipedema, which mainly affects women and causes symptoms like pain, swelling, and tenderness in the legs. Researchers want to understand if a phenomenon called central sensitization, where the nervous system becomes overly sensitive and amplifies pain, is present in people with lipedema. They will compare the experiences of those with lipedema to healthy individuals to learn more about the condition and improve future diagnosis and treatment options.

To participate in this study, you need to be between 18 and 65 years old and either have a confirmed diagnosis of lipedema or be completely healthy without any underlying health issues like diabetes or obesity. Participants will undergo assessments to evaluate their symptoms and pain sensitivity. If you're interested in joining, it's important to be willing to participate and to understand that certain health conditions may disqualify you. Your involvement could help advance our understanding of lipedema and improve care for others living with this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Lipedema; Diagnosis of lipedema Aged between 18 and 65 years Literate Willing to participate in the study
• • 2. control group; Being completely healthy (no internal/metabolic issues such as diabetes, obesity, or hypothyroidism, and no diagnosis of lipedema) BMI ≤ 30 Aged between 18 and 65 years Literate Willing to participate in the study
• Exclusion Criteria:
• • 1. Lipedema group; Under 18 or over 65 years of age Presence of concurrent lymphedema, chronic venous insufficiency, deep vein thrombosis, polyneuropathy, or fibromyalgia Illiterate Not willing to participate in the study
• • 2. Control group; Under 18 or over 65 years of age Presence of concurrent lymphedema, chronic venous insufficiency, deep vein thrombosis, polyneuropathy, fibromyalgia, systemic rheumatic diseases, active cancer, infections, or pregnancy Illiterate Not willing to participate in the study