Exosomes Proteomic for Sjogren's Syndrome and Dry Eye Syndrome

Launched by TAIPEI VETERANS GENERAL HOSPITAL, TAIWAN · Jan 8, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating the role of tiny particles called exosomes in understanding conditions like Sjögren's Syndrome and Dry Eye Syndrome. By looking at the proteins in these exosomes, researchers hope to learn more about how these diseases develop and find better ways to diagnose and treat them. The study is currently looking for participants to help advance our knowledge in this area.

To be eligible for the trial, participants should be between 20 and 75 years old and meet certain health criteria. For those with Dry Eye Syndrome, they need to have a specific test result indicating low tear production. For individuals with Sjögren's Syndrome, they must meet certain diagnostic criteria and not have any serious health issues that could interfere with the study. Healthy individuals without these conditions are also welcome to join. Participants can expect to undergo evaluations to determine their eligibility and may contribute to important findings that could improve future treatments for these eye conditions.

Gender

ALL

Eligibility criteria

• • Dry eye syndrome
• • Inclusion Criteria: aged between 20 and 75 years Schirmer's test less than 10 mm/5 min Exclusion Criteria: Pregnancy With eye inflammation or infectious eye disease Accepted operation of eye Sjögren's syndrome
• • Inclusion Criteria: primary or secondary SS aged between 20 and 75 years fulfilled the 2002 American-European Consensus Criteria for SS (AECG) had no abnormal findings of immune, liver, kidney, or blood function evaluations.
• • Exclusion Criteria: a history of alcohol abuse, diabetes mellitus, or major life-threatening condition pregnancy or breastfeeding steroid pulse therapy within three months prior to the commencement of our study.
• • non AIDDES Healthy Controls
• • Inclusion Criteria: aged between 20 and 75 years without any Chronic disease Exclusion Criteria: any Sjögren's syndrome or Dry eye syndrome.