Study on the Effects of Multimodal Analgesia Regimens on Postoperative Analgesia and Gastrointestinal Function Recovery After Laparoscopic Abdominal Surgery

Launched by XIAGUANG DUAN · Jan 10, 2025

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ClinConnect Summary

This clinical trial is looking into how different pain management methods can help patients recover after laparoscopic abdominal surgery, which is a type of minimally invasive surgery. The study will compare four different ways to control pain: epidural analgesia (a method that delivers pain relief through a catheter in the spine), paravertebral block (another type of nerve block), transversus abdominis plane block (which targets specific abdominal nerves), and patient-controlled intravenous analgesia (where patients can give themselves pain medication through an IV). The main goal is to find out which method not only reduces pain effectively but also helps the digestive system recover faster after surgery.

To participate in this trial, you need to be at least 18 years old and in generally good health (classified as ASA I-III, which means you have a low to moderate risk of complications). You should not have had previous abdominal surgery or any serious health issues that could interfere with the study. Participants will receive one of the pain management treatments after their surgery and will be monitored for their pain levels, recovery progress, and overall hospital stay. This study is not yet recruiting participants, but it aims to gather important information that could improve post-surgery care for patients in the future.

Gender

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Eligibility criteria

• Inclusion Criteria:
• • \>18 years old
• • ASA I-III
• • Ability to understand and voluntarily sign the informed consent form
• • No prior use of long-acting or addictive analgesic drugs before surgery.
• Exclusion Criteria:
• • History of previous abdominal surgery
• • Presence of severe cardiovascular, respiratory, hepatic, renal, neurological, or psychiatric disorders
• • Pre-existing chronic pain conditions
• • Known allergy to any analgesic drugs used in this study
• • Presence of spinal deformities, neurological conditions, or coagulopathy that may affect the performance of regional anesthesia.
• • Pregnant or breastfeeding women
• • Inability to cooperate with study procedures or understand pain rating scales
• • History of opioid abuse or addiction.