Comparing the Effects of Aerobic & Resistance Exercises and Vitamins D & E on Oxidative Stress & Inflammatory Markers Among Patients with Depression

Launched by ZIAUDDIN UNIVERSITY · Jan 9, 2025

Keywords

ClinConnect Summary

A total number of 116 participants will be recruited in the study. After the voluntarily consent, all the participants will be equally divided into four of the treatment group Group-A, B, C and D using envelop method of simple random sampling technique. In addition, a total of 116 sealed envelopes, comprises of 29 envelopes for each group will be presented to the patients. Each patient will be asked to select one envelope of their choice. Upon selection of the envelope, patients will be allocated to the respective group. Thus, each group will comprise of 29 participants Afterwards, pre-asse...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosed patients with mild to moderate depression, aged between 25-35 years referred by Psychiatrist with no other Psychiatric disease attending the respective unit of Creek General Hospital and Dr. Ziauddin Hospital. (Kivani M et al, 2022, Khan B et al., 2022).
• • Individuals both with and without current psychoactive medication (such as antidepressants or anxiolytics) will be enrolled. (O'Sullivan et al., 2023)
• • Participants willing to participate to the intervention.
• Exclusion Criteria:
• • Participants with diagnosed cardiovascular diseases,
• • Participants with pregnant women,
• • Participants with use of beta-blockers,
• • Participants with a history of severe mental illnesses (mentally handicapped),
• • Participants with hypertension, hyperparathyroidism,
• • Participants with current significant substance or alcohol abuse, ongoing burn-out syndrome, and
• • Participants with An elevated suicide risk determined by the Psychiatrist.
• • Participants with Prisoners
• • Participants with chronic diseases such as liver and renal diseases, mal-absorption syndrome, and other diseases that can affect the level of vitamin D.
• • Patients with physical limitations that would prohibit the participation in following exercise protocol.
• • Participants consuming dietary supplements two months prior to the intervention.
• • Participation in regular exercise during the past 6 months (2 days/week).
• • Non cooperative patients and refused to continue the intervention program.