UMMS Sepsis Early Prediction Score (SEPSys) and RESCUE Score Combined Clinical Trial

Launched by UNIVERSITY OF MARYLAND, BALTIMORE · Jan 12, 2025

Keywords

ClinConnect Summary

The UMMS Sepsis Early Prediction Score (SEPSys) and RESCUE Score Combined Clinical Trial is studying two new tools that help doctors predict the risk of serious health problems in hospitalized patients. One tool estimates the risk of developing sepsis, a severe infection that can be life-threatening, within four hours. The other tool predicts the risk of deterioration, which could mean serious issues like cardiac arrest, death, or needing urgent medical attention. The goal is to help healthcare providers become more aware of these risks early on so they can take action to protect patients.

To participate in this trial, patients must be at least 18 years old and admitted to a hospital unit that is part of the University of Maryland Medical System. The trial is looking for patients who are currently receiving care in these inpatient units. However, patients who are already diagnosed with sepsis, are in outpatient settings, or are pediatric patients will not be eligible. If you take part in this study, you can expect that doctors will monitor your vital signs closely after your risk scores indicate a potential problem. This trial is not yet recruiting participants, but it aims to ultimately improve patient care by identifying risks more effectively.

Gender

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Eligibility criteria

• Hospital Unit Inclusion Criteria:
• • Units are part of a member hospital of the University of Maryland Medical System (UMMS)
• • Units treat inpatient patients
• • Units agree to participate in the study
• General Encounter Inclusion Criteria:
• • Encounter is on a participating inpatient unit
• • Encounter is associated with a bedded patient in the hospital
• • Encounter is associated with an adult (at least 18 years of age at time of admission)
• Additional SEPSys Encounter Inclusion Criteria:
• • • Encounter has a SEPSys Score
• Additional RESCUE Encounter Inclusion Criteria:
• • • Encounter has a RESCUE Score
• Exclusion Criteria:
• Hospital Unit Exclusion Criteria:
• • Unit treats exclusively outpatients or is located in an outpatient setting
• • Unit treats primarily or exclusively pediatric patients (patients under the age of 18 years old)
• • Unit treats exclusively psychiatric patients
• Additional SEPSys Encounter Exclusion Criteria:
• • Encounter is with OB for a normal delivery and the patient has yet to give birth. This encounter can become eligible once the patient has given birth.
• • Encounter is admitted with a diagnosis of sepsis
• • Sepsis was already diagnosed during the encounter
• • This encounter will have been eligible until the patient began showing clinical signs or symptoms of sepsis or received a diagnosis of sepsis. Once they have a diagnosis or clinical signs or symptoms of sepsis, their SEPSys Score will no longer be updated. Data will continue to be collected on time of laboratory orders and treatments.
• Additional RESCUE Encounter Exclusion Criteria:
• • • Encounter is admitted with a high RESCUE Score (RESCUE Score of 4)