Molecular Characteristics of Hepatitis B Virus Integration, Mutation, and Drug Resistance

Launched by BEIJING FRIENDSHIP HOSPITAL · Jan 13, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the characteristics of the Hepatitis B virus (HBV) in patients with chronic Hepatitis B (CHB). The researchers are looking at how the virus changes over time, how it might resist treatments, and how these changes relate to patient outcomes like liver disease or cancer. There are two groups of participants: one group is made up of patients who are receiving antiviral treatments and are monitored regularly, while the other group includes patients who have not received treatment, with data collected at a single time point. By analyzing blood and liver tissue samples, the study aims to better understand the virus's genetic makeup and its impact on health.

To be eligible for this trial, patients need to be positive for Hepatitis B surface antigen and have complete medical records along with blood or liver tissue samples available. Unfortunately, patients without these samples cannot participate. Those who join the study can expect to contribute to important research that may improve the understanding of chronic Hepatitis B and inform future treatments. The trial is currently recruiting participants of all genders aged 65 and older.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with hepatitis B surface antigen positive.
• • Patients who have complete demographic information, clinical data and retained blood samples or liver tissue samples
• Exclusion Criteria:
• • Subject who without blood samples or liver tissue samples