Autophagy/Apoptosis Balance in Placental Vascular Pathologies

Launched by CENTRE HOSPITALIER UNIVERSITAIRE DE NĪMES · Jan 15, 2025

Keywords

ClinConnect Summary

This clinical trial, titled "Autophagy/Apoptosis Balance in Placental Vascular Pathologies," is studying how certain cellular processes in the placenta may contribute to pregnancy complications like pre-eclampsia and growth issues in the baby. Scientists are particularly interested in understanding how the balance between cell survival and cell death is affected during these complications. By examining these processes, the researchers hope to find new ways to identify and manage risks for mothers and their babies during pregnancy.

To participate in this trial, women must be pregnant and experiencing complications related to the placenta, such as pre-eclampsia or reduced growth of the baby, and must be delivering at Nîmes University Hospital. Participants should be able to provide informed consent and have health insurance. Women with multiple pregnancies or existing health conditions, like high blood pressure before pregnancy, are not eligible. While the trial is not yet recruiting, those who qualify can expect to contribute to important research that could lead to better understanding and prevention of serious pregnancy complications.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Pregnant women developing a placental vascular complication (preeclampsia and/or intrauterine growth retardation), hospitalized and delivering at Nîmes University Hospital.
• • Pregnant woman with free and informed consent.
• • Pregnant woman affiliated with and/or benefiting from a health insurance scheme.
• Exclusion criteria:
• • Multiple pregnancy.
• • Presence of hypertension and/or proteinuria prior to pregnancy.
• • Participant in an interventional drug study.
• • Persons in a period of exclusion determined by another study.
• • Persons under court protection, guardianship or curatorship.
• • Persons unable to give consent.
• • Persons for whom it is impossible to give informed information.