Assessment of Medrol Dosepak to Reduce Opioid Consumption in Foot and Ankle Surgical Patients

Launched by EMORY UNIVERSITY · Jan 13, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a medication called Medrol Dosepak, which is a low-dose steroid taken for 6 days, on patients who are having surgery on their feet or ankles. The main goal is to see if this medication can help reduce pain, nausea, and the amount of opioids (strong painkillers) needed after surgery. Researchers also want to learn if the medication has any impact on complications after surgery and how patients feel about their recovery.

To participate in this study, you need to be an Emory Orthopedic patient scheduled for foot or ankle surgery. However, certain conditions might exclude you, such as having serious injuries to other parts of your body, infections, or a history of substance abuse. If you join the trial, you can expect to take the medication for a week and be monitored closely by the research team for your recovery progress and any side effects. This study is currently looking for participants, and it welcomes individuals of any gender between the ages of 18 and 99.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • -Emory Orthopedic patients undergoing foot and ankle surgery
• Exclusion Criteria:
• • Concurrent or significant injuries to other bones or organs
• • Local infections
• • History of alcohol or medical abuse, including prior opioid abuse
• • Smoking
• • History of severe heart disease, renal failure, liver dysfunction, active peptic ulcer disease, diabetes, rheumatoid arthritis, neurological or psychiatric diseases that could influence pain perception
• • Pre-existing immune suppression
• • Those deemed possibly non-compliant by the study team and,
• • All vulnerable populations (those unable to give consent, juveniles, pregnant women, prisoners, cognitively impaired and non-English speaking).