Clinical Performance of Resin Composite Restoration After Dentin Biomodification by Grape Seed Extract in Deep Carious Lesions.

Launched by CAIRO UNIVERSITY · Jan 13, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how well a dental treatment works for people with deep cavities in their back teeth. The researchers want to see if using a natural substance called grape seed extract can improve the way a special filling material sticks to the tooth after some soft, decayed parts are carefully removed. This study will focus on adults aged 22 to 42 who have certain types of deep cavities, but not everyone will be eligible to participate.

To join the study, participants must have good oral hygiene and be able to follow up after the treatment. They should not have any allergies to the materials used, be pregnant, or have any serious health issues. If you take pain medications regularly or have certain dental problems like previous fillings or severe pain, you might not be able to participate. Those who do join can expect to receive a filling and will have their tooth's health monitored over time to see how well the treatment works.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Patient-related criteria:
• • 1. Adult patients (age: 22-42 years) of both genders.
• • 2. Good oral hygiene.
• • 3. Willing to sign the informed consent.
• • 4. Co-operative patients who accept the follow-up period.
• * Tooth-related criteria:
• • 1. Posterior permanent caries (ICDAS 5\&6).
• • 2. Radiographically, caries is extending 50% of dentine with a radiopaque layer between the carious lesion and the pulp chamber.
• • 3. Sensible teeth according to cold pulp test.
• • 4. Negative response in percussion test.
• Exclusion Criteria:
• * Patient-related criteria:
• • 1. Allergy to any of the restorative materials.
• • 2. Patients undergoing orthodontic treatment with fixed appliances.
• • 3. Pregnant women.
• • 4. Patients with debilitating systemic diseases.
• • 5. Patient who frequently use analgesic or any drugs that could mask the pain.
• * Tooth-related criteria:
• • 1. Teeth with previous restorations.
• • 2. Spontaneous pain or prolonged pain (more than 15 s) after sensitivity test (cold test), which would indicate irreversible pulpitis.
• • 3. Negative sensibility tests, periapical radiolucencies and sensitivity to axial or lateral percussion.
• • 4. Mobile teeth, indicating periodontal disease or trauma.
• • 5. External or internal resorption.
• • 6. Chipped teeth or Cuspal loss