Power Exercise for Stroke Recovery: The POWER Pilot Trial (POWER-P)
Launched by MCMASTER UNIVERSITY · Jan 16, 2025
Trial Information
Current as of August 20, 2025
Not yet recruiting
Keywords
ClinConnect Summary
The POWER Pilot Trial (POWER-P) is a study designed to see if a special kind of exercise program can help people recover from stroke. After a stroke, many individuals struggle with weakness, making everyday activities like walking and balancing difficult. This trial will focus on a 10-week power training program, which aims to improve strength and muscle power in people who have had a stroke. This approach is different from regular strength training because it emphasizes faster movements, which may be more beneficial for recovery.
To participate in this trial, you need to be at least 18 years old, have had a stroke at least six months ago, and be able to walk at least 10 meters, either with or without help. You should also have mild to moderate stroke severity and not have significant cognitive difficulties. Participants will be randomly assigned to either the POWER training program or a standard strength training program, which is less intense and does not focus on building muscle power. Throughout the trial, researchers will monitor how well each group improves in walking, strength, and balance. This study will help shape future research to find the best ways to support stroke recovery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. ≥18 years old
- • 2. ≥6 months poststroke,
- • 3. able to walk \>10 meters with or without an assistive device
- • 4. have mild to moderate stroke severity (modified Rankin Scale ≤3)
- • 5. without significant cognitive impairment that would preclude safe exercise, screened via Montreal Cognitive Assessment-Blind score \<18
- Exclusion Criteria:
- • 1. Any contraindications to exercise for people with cardiovascular disease, such as unstable angina, uncontrolled hypertension, orthostatic blood pressure with exercise, or uncontrolled arrhythmias or
- • 2. Actively engaged in or have made plans to engage in stroke rehabilitation services
About Mcmaster University
McMaster University, a leading research institution located in Hamilton, Ontario, Canada, is renowned for its innovative approach to education and its commitment to advancing healthcare through rigorous clinical research. The university's diverse research programs are supported by a multidisciplinary team of experts dedicated to improving patient outcomes and public health. With a strong emphasis on evidence-based medicine, McMaster University actively engages in clinical trials that explore new therapies, interventions, and health technologies, fostering collaboration among researchers, healthcare professionals, and industry partners to translate findings into real-world applications.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Hamilton, Ontario, Canada
Kelowna, British Columbia, Canada
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported