Comparison of High and Moderate Intensity Statins in Achieving the Target LDL-C Level After Acute Coronary Syndrome

Launched by KHYBER MEDICAL UNIVERSITY PESHAWAR · Jan 16, 2025

Keywords

ClinConnect Summary

This clinical trial is examining how well high-intensity statins compare to moderate-intensity statins in lowering bad cholesterol (LDL-C) levels in patients who have experienced acute coronary syndrome (ACS), a serious heart condition. The main goal is to see if moderate-intensity statins can be just as effective as the stronger option, especially for those who may have a higher risk of side effects from taking stronger medications. This information could help doctors make better treatment choices and also ease the financial burden on patients.

To participate in this study, individuals should be between 25 and 85 years old, regardless of gender, and must have been diagnosed with acute coronary syndrome. However, those who have had serious reactions to statins in the past, currently have liver problems, are pregnant or breastfeeding, or are already taking statins will not be eligible. If you enroll, you can expect to contribute to important research that may change how heart conditions are treated in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Participants aged between 25 and 85 years.
• • Both males and females.
• • Diagnosed with acute coronary syndrome as defined in the operational definitions.
• Exclusion Criteria:
• • History of adverse reactions to statins (e.g., hypersensitivity, myopathy, acute renal failure).
• • Current acute liver disease.
• • Pregnant or breastfeeding women.
• • Participants already on statin therapy