Activation Failure of Knee Extensors After Anterior Cruciate Ligament Rupture Depending on the Contraction Mode

Launched by LA TOUR HOSPITAL · Jan 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how an injury to the anterior cruciate ligament (ACL) affects the ability of patients to activate their knee muscles during different types of contractions. The researchers want to find out if the way the muscles are activated varies based on the type of contraction and how this impacts recovery after an ACL injury. By doing this, they hope to provide better recommendations for rehabilitation, whether patients undergo surgery or receive conservative treatment.

To participate in this trial, individuals need to be between 18 and 50 years old and have recently injured their ACL or be healthy individuals who regularly engage in sports. Participants will be involved in two sessions: one shortly after their injury and another several months later. During these sessions, they will undergo tests to measure their muscle activation. It's important to note that individuals with certain medical conditions, previous knee injuries, or those who are pregnant are not eligible to join. Overall, this study aims to improve our understanding of recovery from ACL injuries and help guide rehabilitation practices.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• A. ACL-injured groups (surgically or conservatively treated):
• • 1. Age between 18 and 50 years
• • 2. Free, informed consent signed by the participant and the investigator.
• • 3. Session 1: Delay of 2 to 6 weeks after injury, with a quiet knee (range of motion 110- 0°, minimal effusion, maximal contraction pain ≤ 2/10)
• • 4. Session 2: Duration of 36 to 42 weeks after injury, with a quiet knee (range of motion 110-0°, minimal effusion, maximal contraction pain ≤ 2/10)
• • 5. Independent person (Unprotected: under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision)
• B. ControlGroup:
• • 1. Age between 18 and 50 years
• • 2. Free, informed consent signed by the participant and the investigator.
• • 3. Sport practitioners: at least once per week practicing activities like collective sports, racket sports, combat sports, skiing, or on-loading activities with changing of directions.
• • 4. Independent person (Unprotected: under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision)
• Exclusion Criteria:
• • 1. Subjects fitted with an implanted electronic device such as a cardiac pacemaker 2. Professional athlete 3. Pregnant women 4. Subject with systemic pathology or treatment affecting the musculoskeletal system 5. Subject with a history of neurological pathology or traumatic pathology, or pathology that required orthopedic treatment and/or surgery of the knee, hip and/or lumbar spine 6. Contraindication to isokinetic testing: incapacitating pain, evolving pathological process, non- healed fracture, unbalanced cardiovascular pathology (angina pectoris, arterial hypertension) 7. Contralateral knee injury 8. Subject inability to follow procedures or insufficient knowledge of project language 9. Data acquisition issue or injury during testing