Immediate Effects of Lipid-Based and Non-Lipid Artificial Tears on Corneal Aberrations

Launched by UNIVERSITY OF SEVILLE · Jan 14, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how two different types of artificial tears affect the surface of the eye, specifically focusing on something called corneal aberrations, which can impact vision. The researchers will compare a lipid-based tear that contains mineral oil and a non-lipid tear that only has hydroxypropyl guar. Healthy participants will receive one type of tear in each eye and then have their eyes checked 15 minutes later to see how the tears have changed their eye's surface.

To be eligible for this study, participants should be healthy adults aged 18 to 35, with good vision (20/20 or better), and no history of eye problems, surgeries, or contact lens use. They should also be willing to follow the study procedures. This study is not yet recruiting, so it's important for interested individuals to keep an eye out for when they can join. Overall, participants will play a key role in helping researchers understand the effects of different artificial tears on eye health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy individuals aged 18 to 35 years. No prior history of ocular surface disease, refractive surgery, or contact lens wear.
• • Corrected visual acuity of 20/20 or better. Ability to provide informed consent. Willingness to comply with study procedures, including instillation of artificial tears and follow-up measurements.
• Exclusion Criteria:
• • History of any ocular surgery or trauma within the past six months. Use of any systemic or topical medications that may affect ocular surface stability or tear film.
• • Any active or chronic ocular infection, inflammation, or other pathology. Known hypersensitivity or allergy to any components of the artificial tears. Pregnancy or breastfeeding. Participation in another clinical trial within the last 30 days.