Maternal Abdominal Morphology Assessment

Launched by UNIVERSITY OF TEXAS AT AUSTIN · Jan 14, 2025

Keywords

ClinConnect Summary

The MAMA study, which stands for Maternal Abdominal Morphology Assessment, is looking into how pregnancy affects the size and function of the pancreas in mothers and their babies, especially regarding diabetes. Previous research has shown that people with diabetes often have smaller pancreas sizes, but during pregnancy, the pancreas appears to grow. This study aims to understand these changes better and how they relate to maternal diabetes.

If you're a woman aged 18 to 54 and are less than 14 weeks pregnant with a single baby, you might be eligible to participate in the MAMA study. Participants will be followed throughout their pregnancy and for one year after giving birth. You'll be asked to stay in the Austin area during that time. As a participant, you can expect to undergo some assessments, including MRI scans, to help researchers learn more about the pancreas. It's important to note that certain conditions, like having implants that could interfere with MRI or being claustrophobic, might prevent you from participating. This study offers a chance to contribute to important research that could improve our understanding of pregnancy and diabetes.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Pregnant women, with a singleton gestation
• • Age 18 - 54 years at screening
• • Gestational age \< 14 weeks
• • Willing to commit to 1 year postpartum follow up
• • Planning to remain in geographical vicinity of Austin for 1 year after delivery
• Exclusion Criteria:
• • Presence of any mechanically or magnetically activated implants
• • Claustrophobia
• • Other contraindication for MRI
• • BMI ≥ 35.0 or maximum width less than 48 cm (necessary to fit within the MRI field of view)