Clinical Impact of Non-invasive Neurally Adjusted Ventilatory Assist in Very Preterm Infants

Launched by KOREA UNIVERSITY ANAM HOSPITAL · Jan 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help very premature babies breathe called Non-invasive Neurally Adjusted Ventilatory Assist, or NIV-NAVA. The researchers want to see how this method affects the babies' health in the short term and their brain development in the long run. They are currently looking for very preterm infants, specifically those born between 28 weeks and 31 weeks and 6 days of gestation, who did not need a breathing tube immediately after birth.

To be part of the study, babies must meet these criteria: they should be born within the specified weeks and not require a breathing tube right after birth. However, infants born before 28 weeks or those needing immediate breathing support, as well as those with certain health conditions affecting their lungs or heart, cannot participate. Parents will be asked for their permission to enroll their baby in the study. If chosen, families can expect close monitoring and support as researchers gather information on how NIV-NAVA may improve breathing and development in these vulnerable infants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Preterm infants born between 27 weeks 0 days to 31 weeks 6 days of gestation
• • Preterm infants who require respiratory support within the first 48 hours of life
• Exclusion Criteria:
• • Preterm infants who die within the first 48 hours of life
• • Preterm infants who do not require any respiratory support within the first 48 hours of life.
• • Preterm infants with congenital anomalies affecting the lungs, heart, or other organs that could influence breathing
• • Infants whose parents do not consent to participate in the study